Cells organize themselves to maintain proper shape, structure, and size during growth and division for their cellular functions. However, how these cellular organizations coordinate with the cell cycle is not well understood. This review focuses on cell morphogenesis and size of the membrane-bound nucleus in the fission yeast Schizosaccharomyces pombe. Growth polarity, an important factor for cell morphogenesis, in rod-shaped fission yeast is restricted to the cell tips and dynamically changes depending on the cell cycle stage. Furthermore, nuclear size in fission yeast is proportional to the cell size, resulting in a constant ratio between nuclear volume and cellular volume (N/C ratio). This review summarizes the signaling pathway(s) involved in growth polarity control and key factors involved in N/C ratio control and provides their roles in coordination between cell organization and the cell cycle.

中文翻译：

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控制细胞组织及其与细胞周期的协调。

细胞组织起来以在其细胞功能的生长和分裂过程中保持适当的形状，结构和大小。但是，这些细胞组织如何与细胞周期协调尚不清楚。这篇综述集中在裂殖酵母粟酒裂殖酵母中的细胞形态发生和膜结合核的大小。杆状裂变酵母中的生长极性是细胞形态发生的重要因素，它的作用仅限于细胞尖端，并根据细胞周期阶段动态变化。此外，裂变酵母中的核大小与细胞大小成正比，导致核体积和细胞体积之间的比率恒定（N / C比）。