With respect to the unknowns of pathophysiology of Alzheimer’s Disease (AD)-, and Parkinson’s Disease (PD)-like neurodegenerative disorders, natural product research is still one of the valid tools in order to provide alternative and/or better treatment options. At one hand, various extracts of herbals provide a combination of actions targeting multiple receptors, on the other hand, the discovery of active natural products (i.e., secondary metabolites) generally offers alternative chemical structures either ready to be employed in clinical studies or available to be utilized as important scaffolds for the design of novel agents. Regarding the importance of certain enzymes (e.g. cholinesterase and monoamine oxidase B), for the treatment of AD and PD, we have surveyed the natural product research within this area in the last decade. Particularly novel natural agents discovered within this period, concomitant to novel biological activities displayed for known natural products, are harmonized within the present study.

关于阿尔茨海默氏病（AD）和帕金森氏病（PD）样神经退行性疾病的病理生理学的未知数，天然产物研究仍是有效的工具之一，以提供替代和/或更好的治疗选择。一方面，各种草药提取物提供了针对多种受体的多种作用，另一方面，活性天然产物（即次生代谢产物）的发现通常提供了可供临床研究使用或可供选择的化学结构。用作设计新型药物的重要支架。关于某些酶（例如胆碱酯酶和单胺氧化酶B）对于治疗AD和PD的重要性，我们在过去十年中对该领域的天然产物研究进行了调查。