I analyzed the model that suggests that an RNA ring might have been the progenitor of the tRNA molecule (Demongeot and Moreira in J Theor Biol 249:314-324, 2007; Demongeot and Seligmann in J Mol Evol 1-23, 2019a; Demongeot and Norris in Life 9(2):51, 2019). In particular, I analyze three ways in which this precursor, especially in its RNA hairpin form, could have evolved into the complete tRNA molecule. These three modalities are based on multiple duplication events, and therefore, appear to be less parsimonious than that which assumes that this molecule originated through one duplication of a single hairpin structure. The conclusion is, therefore, that the latter model appears to be preferable with respect to that of the RNA ring, also because there are many independent observations and some of a historical nature that would corroborate it in an extraordinary way.

中文翻译：

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RNA环不是tRNA分子的祖先。

我分析了表明RNA环可能是tRNA分子的祖先的模型（Demongeot和Moreira在J Theor Biol 249：314-324，2007; Demongeot和Seligmann在J Mol Evol 1-23，2019a; Demongeot and Norris in Life 9（2）：51，2019）。特别是，我分析了该前体（尤其是其RNA发夹形式）进化成完整的tRNA分子的三种方式。这三种模式是基于多个重复事件的，因此，与假设该分子起源于单个发夹结构的一次重复的假设相比，它似乎没有那么简单。因此，得出的结论是，相对于RNA环，后者的模型似乎更可取，