BACKGROUND Anxiety is a common and distressing problem after stroke. AIMS To undertake an updated systematic review and meta-analysis of observational studies of anxiety after stroke and integrate the findings with those reported previously. SUMMARY OF REVIEW Multiple databases were searched in May 2018 and 53 new studies were included following dual independent sifting and data extraction. These were combined with 44 previous studies to form a combined data set of 97 studies, comprising 22,262 participants. Studies using interview methods were of higher quality. Rates of anxiety by interview were 18.7% (95% confidence interval 12.5, 24.9%) and 24.2% (95% confidence interval 21.5, 26.9%) by rating scale. Rates of anxiety did not lower meaningfully up to 24 months after stroke. Eight different anxiety subtypes were also reported. CONCLUSIONS This review confirms that anxiety occurs in around one in four patients (by rating scale) and one in five patients (by interview). More research on anxiety subtypes is needed for an informed understanding of its effects and the development of interventions.

中文翻译：

---

中风后焦虑的频率：观察性研究的更新系统评价和荟萃分析。

背景焦虑是中风后常见且令人痛苦的问题。目的 对中风后焦虑的观察性研究进行更新的系统评价和荟萃分析，并将结果与​​先前报告的结果相结合。综述总结 2018 年 5 月检索了多个数据库，在双重独立筛选和数据提取后纳入了 53 项新研究。这些与之前的 44 项研究相结合，形成了 97 项研究的组合数据集，包括 22,262 名参与者。使用访谈法的研究质量更高。按评定量表，访谈的焦虑率分别为 18.7%（95% 置信区间 12.5、24.9%）和 24.2%（95% 置信区间 21.5、26.9%）。中风后 24 个月内，焦虑率并未显着降低。还报告了八种不同的焦虑亚型。结论 本综述证实，大约四分之一的患者（通过评分量表）和五分之一的患者（通过访谈）发生焦虑。需要对焦虑亚型进行更多研究，以了解其影响和干预措施的发展。