Resistant starch (RS) consumption has beneficial effects on health, such as reduced postprandial blood glucose levels. In this study, we evaluated the effect of a 14-day diet containing RS on α-glucosidase activity and the expression of genes related to carbohydrate digestion/absorption in rats. We examined whether the effects of RS persist when the rats were shifted to a control diet. The results suggest that RS consumption reduces α-glucosidase activity and Mgam, Si and Sglt1 mRNA levels in the proximal jejunum. In addition, RS consumption appeared to influence the serum GIP level, up to 2 days after the animals were shifted to a control diet. To our knowledge, this is the first report that RS has a sustained effect on gut hormone expression and the expression of genes related to carbohydrate digestion/absorption in the proximal jejunum.

食用抗性淀粉（RS）对健康有益，例如降低餐后血糖水平。在这项研究中，我们评估了含RS的14天饮食对大鼠α-葡萄糖苷酶活性以及与碳水化合物消化/吸收相关的基因表达的影响。我们检查了当大鼠转为对照饮食时，RS的作用是否持续。结果表明，食用RS降低了α-葡萄糖苷酶的活性，降低了Mgam，Si和Sglt1空肠近端的mRNA水平。另外，在动物转为对照饮食后最多2天，食用RS似乎会影响血清GIP水平。据我们所知，这是第一个关于RS对空肠近端肠内激素表达以及与碳水化合物消化/吸收相关的基因表达具有持续影响的报道。