Genetic Predisposition to High-Altitude Pulmonary Edema.,High Altitude Medicine & Biology

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Genetic Predisposition to High-Altitude Pulmonary Edema.
High Altitude Medicine & Biology ( IF 1.6 ) Pub Date : 2020-03-17 , DOI: 10.1089/ham.2019.0083
Christina A Eichstaedt _{1,

2,

3} , Heimo Mairbäurl _{3,

4} , Jie Song _{1,

2,

5} , Nicola Benjamin _{1,

3} , Christine Fischer ₂ , Christoph Dehnert ₆ , Kai Schommer ₄ , Marc M Berger ₇ , Peter Bärtsch ₄ , Ekkehard Grünig _{1,

3} , Katrin Hinderhofer ₂

Affiliation

Background: Exaggerated pulmonary arterial hypertension (PAH) is a hallmark of high-altitude pulmonary edema (HAPE). The objective of this study was therefore to investigate genetic predisposition to HAPE by analyzing PAH candidate genes in a HAPE-susceptible (HAPE-S) family and in unrelated HAPE-S mountaineers.

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