Objectives: The most common macrolide resistance mechanisms in streptococci are the presence of methylase encoding genes ermB and ermTR or the presence of efflux encoded by mef genes. In the present study we aimed to show the effects of the ermTR gene under isogenic conditions on the activities of macrolides and lincosamides in streptococci.

中文翻译：

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克隆的ermTR基因在化脓性链球菌NZ131中赋予低水平的红霉素和高水平的克林霉素抗性。

目的：链球菌中最常见的大环内酯类耐药机制是存在甲基化酶编码基因ermB和ermTR或存在由mef基因编码的外排。在本研究中，我们旨在显示ermTR基因在等基因条件下对链球菌中大环内酯类和林可酰胺类活性的影响。