Synthetic biology can greatly aid the investigation of fundamental regulatory mechanisms and enable their direct deployment in the host organisms of choice. In the field of plant hypoxia physiology, a synthetic biology approach has recently been exploited to infer general properties of the plant oxygen sensing mechanism, by expression of plant‐specific components in yeast. Moreover, genetic sensors have been devised to report cellular oxygen levels or physiological parameters associated with hypoxia, and orthogonal switches have been introduced in plants to trigger oxygen‐specific responses. Upcoming applications are expected, such as genetic tailoring of oxygen‐responsive traits, engineering of plant hypoxic metabolism and oxygen delivery to hypoxic tissues, and expansion of the repertoire of genetically encoded oxygen sensors.

中文翻译：

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缺氧的合成生物学。

合成生物学可以大大有助于基本调控机制的研究，并使它们可以直接部署在所选的宿主生物中。在植物缺氧生理学领域，最近已开发出一种合成生物学方法，通过在酵母中表达植物特异性成分来推断植物氧传感机制的一般特性。此外，已经设计出遗传传感器来报告与低氧有关的细胞氧水平或生理参数，并且已经在植物中引入了正交开关以触发氧特异性反应。预计将有新的应用，例如对氧响应性状的遗传定制，植物低氧代谢的工程设计和向低氧组织的氧输送，以及基因编码氧传感器的功能扩展。