Zika virus (ZIKV) is an emerging arbovirus that causes a mosquito-borne disease. Although infection with ZIKV generally leads to mild disease, its recent emergence in the Americas has been associated with an increase in the development of the Guillain-Barré syndrome in adults, as well as with neurological complications, in particular congenital microcephaly, in new-borns. Over the five past years, through the combined efforts of the scientific community, comprehensive remarkable progress aimed at deciphering the clinical, virological, physiopathological, and immunological features of ZIKV infection. This review highlights some of the most recent advances in our understanding of the role of cytokines and chemokines in ZIKV infection, and discusses potential links to pathogenesis.

中文翻译：

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寨卡病毒在细胞因子风暴的眼中。

寨卡病毒（ZIKV）是一种新兴的虫媒病毒，可引起蚊媒疾病。尽管ZIKV感染通常会导致轻度疾病，但它在美洲的近来出现与成人Guillain-Barré综合征的发展增加以及新生儿的神经系统并发症（尤其是先天性小头畸形）有关。在过去的五年中，通过科学界的共同努力，旨在破译ZIKV感染的临床，病毒学，生理病理学和免疫学特征的综合性显着进展。这篇综述着重介绍了我们对细胞因子和趋化因子在ZIKV感染中的作用的理解方面的最新进展，并讨论了与发病机理的潜在联系。