BACKGROUND Occluded major intracranial arteries can spontaneously recanalize in patients with acute ischemic stroke mainly due to embolic mechanisms. However, it remains unknown whether recanalization can occur in perforating arteries, such as lenticulostriate arteries. Therefore, in the present study, we assessed changes suggesting recanalization of the lenticulostriate arteries in patients with acute ischemic stroke of the lenticulostriate artery territory using high-resolution magnetic resonance angiography (HR-MRA) at 7T. METHODS We prospectively examined 39 consecutive patients with acute infarcts confined within the lenticulostriate artery territory. Using a 7T scanner during the acute period and one month thereafter, we evaluated imaging findings indicating the recanalization of the relevant lenticulostriate arteries, following which we examined differences in other imaging findings and clinical characteristics between patients with/without recanalization. RESULTS HR-MRA findings suggestive of recanalization (i.e. patent lenticulostriate arteries within acute infarct lesions with/without hemorrhagic changes) were observed in 8 (25%) of 32 patients who were eligible for analyses. These findings were detected in three and five patients on the baseline and follow-up images, respectively. The lengths of relevant lenticulostriate arteries on the follow-up MRA were significantly larger in patients with recanalization than in those without (P = 0.01). However, there were no significant differences in the infarct volume or clinical outcomes between the recanalization and non-recanalization groups. CONCLUSION HR-MRA at 7T revealed that recanalization of the relevant lenticulostriate arteries can occur in patients with acute ischemic stroke confined to the lenticulostriate artery territory.

中文翻译：

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使用 7T 高分辨率 MRA 评估急性缺血性卒中相关豆纹动脉的再通。

背景在急性缺血性卒中患者中，主要由于栓塞机制，闭塞的颅内大动脉可以自发再通。然而，在穿通动脉（例如豆纹动脉）中是否会发生再通仍然未知。因此，在本研究中，我们使用高分辨率磁共振血管造影 (HR-MRA) 7T 评估了豆纹动脉区域急性缺血性卒中患者豆纹动脉再通的变化。方法 我们前瞻性地检查了 39 名连续的急性梗塞患者，这些患者的急性梗死局限在豆纹动脉区域内。在急性期和之后一个月使用 7T 扫描仪，我们评估了表明相关豆纹动脉再通的影像学结果，随后，我们检查了有/无再通患者之间其他影像学表现和临床特征的差异。结果 在符合分析条件的 32 名患者中，有 8 名 (25%) 观察到 HR-MRA 结果提示血管再通（即急性梗塞病灶内的豆纹状动脉未闭，伴有/不伴有出血性改变）。这些发现分别在三名和五名患者的基线和后续图像中检测到。随访 MRA 中相关豆纹动脉长度显着大于未再通患者（P = 0.01）。然而，再通组和非再通组之间的梗死体积或临床结果没有显着差异。