Pediatric low-grade gliomas (LGGs) are found in approximately 1-3% of patients with childhood epilepsy that is often medically refractory. Magnetic resonance guided laser interstitial thermal therapy (MRgLITT) is a minimal access technique FDA-approved since 2007 to ablate soft tissue lesions including brain tumors and seizure foci in children. The authors describe the case of an 11-year-old boy who presented with focal right-sided seizures and was found to have a growing left insular mass determined to be a WHO grade II diffuse astrocytoma. After the initial open resection using frontotemporal craniotomy with transsylvian approach, gross total resection was achieved; however, the tumor recurred, as did the seizures. Six months postoperatively, the patient underwent laser ablation with MRgLITT for the recurrent tumor with complete removal. At both 1- and 6-months post re-operation, he has remained seizure free. MRgLITT management of LGG allows for both successfully reducing tumor burden and the amelioration of secondary seizures.

中文翻译：

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激光间隙热疗后癫痫发作免于复发性岛状低度神经胶质瘤。

小儿低度神经胶质瘤（LGG）在大约1-3％的儿童癫痫患者中发现，这些患者通常在医学上是难治的。自2007年以来，磁共振引导激光间质热疗法（MRgLITT）是FDA批准的一种最小接入技术，用于消融儿童的软组织病变，包括脑部肿瘤和癫痫发作。作者描述了一个11岁男孩的案例，该男孩表现出局灶性右侧癫痫发作，并且发现其被确定为WHO II级弥漫性星形细胞瘤的左岛状肿块正在增长。使用额颞开颅手术并经经颅侧入路进行初次开放切除后，可实现总切除。然而，肿瘤复发，癫痫发作也一样。术后六个月，该患者接受了MRgLITT激光消融术以彻底切除复发性肿瘤。再次手术后1个月和6个月，他都没有癫痫发作。LGG的MRgLITT管理既可以成功减轻肿瘤负担，又可以改善继发性癫痫发作。