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The role of KLF14 in multiple disease processes.
Biofactors ( IF 5.0 ) Pub Date : 2020-01-11 , DOI: 10.1002/biof.1612
Xiaoyan Chen 1 , Wenjie Shi 2 , Heng Zhang 1
Affiliation  

Kruppel‐like factor 14 (KLF14) is a newly identified member of the KLF family. Expression of KLF14 is induced by TGF‐β in intrauterine and ectodermal tissue. Initial researches on KLF14 focused on its role in lipid and glucose metabolism. In recent years, however, the role of KLF14 in regulating cell signaling pathways, cell proliferation and differentiation has been explored. Moreover, the research has gradually extended into the field of tumorigenesis and immune regulation. This paper aims to briefly review the functions of KLF14 in physiologyical and pathological process.

中文翻译:

KLF14在多种疾病过程中的作用。

Kruppel样因子14(KLF14)是KLF家族的新成员。TGF-β在子宫内和表皮组织中诱导KLF14的表达。KLF14的初步研究集中于其在脂质和葡萄糖代谢中的作用。然而,近年来,已经探索了KLF14在调节细胞信号传导途径,细胞增殖和分化中的作用。此外,研究已逐渐扩展到肿瘤发生和免疫调节领域。本文旨在简要回顾KLF14在生理和病理过程中的功能。
更新日期:2020-01-11
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