The complexation of anionic liposomes and polymeric microspheres with grafted polycationic chains (spherical polycationic brushes) is studied. Three types of liposomes with the same molar amount of the anionic lipid are used, namely, liquid liposomes with a high mobility of lipids within the bilayer, solid liposomes with limited lateral and transmembrane mobility of lipid molecules, and solid liposomes with embedded cholesterol. All liposomes efficiently adsorb on the surface of brushes. Upon adsorption, solid liposomes begin to “leak,” that is, to release water-soluble contents in the surrounding solution, whereas solid liposomes with the embedded cholesterol preserve their integrity. Cholesterol-containing liposomes are of interest for obtaining multiliposomal containers with encapsulated biologically active compounds, catalysts, diagnostic agents, etc.

研究了阴离子脂质体和聚合物微球与接枝的聚阳离子链（球形聚阳离子刷）的络合。使用具有相同摩尔量的阴离子脂质的三种类型的脂质体，即在双层内具有高脂质迁移率的液体脂质体，脂质分子的横向和跨膜迁移率有限的固体脂质体和具有嵌入胆固醇的固体脂质体。所有脂质体均有效吸附在刷子表面。吸附后，固体脂质体开始“泄漏”，即释放周围溶液中的水溶性内容物，而具有嵌入胆固醇的固体脂质体则保持其完整性。含有胆固醇的脂质体对于获得带有封装的生物活性化合物，催化剂，