Abstract A new method based on low temperature partitioning extraction (LTPE) with gas chromatography triple quadrupole tandem mass spectrometry (GC-MS/MS) detection was proposed and applied to analysis of polycyclic aromatic hydrocarbons (PAHs) in primary school students’ urine. Both urinary hydroxy PAHs (OH-PAHs) and atmospheric PAHs were determined to discuss the relationship of air pollution and children internal exposure. The analytical results showed that in the total of 50 children's urine samples, 10 of 16 urinary PAHs were detected in all samples, and the concentrations of detected PAHs congener ranged from N.D. to 2418 ng/L, with the highest level of naphthalene (Nap). There were significant correlations between phenanthrene (Phe) and all the other PAHs congeners; and when the concentrations of PAHs in the air at higher levels, urinary Nap was correlated with more urinary PAHs congeners and positively correlated with hydroxy naphthalene. Furthermore, there existed a consistent time trend between the medium concentration of Nap, acenaphthene (Ace) in the urine samples and in the air samples. This study associated the PAHs air pollution with children internal exposure, and together with previously reported studies it could associate the PAHs air pollution with human health effect.

中文翻译：

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低温分配萃取-气相色谱三重四极杆串联质谱法测定儿童尿液中未代谢的多环芳烃

摘要 提出了一种基于低温分配萃取（LTPE）-气相色谱三重四极杆串联质谱（GC-MS/MS）检测的新方法，并将其应用于小学生尿液中多环芳烃（PAHs）的分析。测定尿羟基多环芳烃（OH-PAHs）和大气多环芳烃，讨论空气污染与儿童体内暴露的关系。分析结果表明，在50份儿童尿液样本中，所有样本中检测到16种尿液PAHs中的10种，PAHs同源物浓度范围为ND至2418 ng/L，其中萘（Nap）含量最高. 菲 (Phe) 与所有其他 PAH 同系物之间存在显着相关性；当空气中多环芳烃的浓度较高时，尿Nap与更多的尿PAHs同源物相关，与羟基萘呈正相关。此外，尿液样本和空气样本中Nap、苊（Ace）的中等浓度之间存在一致的时间趋势。本研究将多环芳烃空气污染与儿童体内暴露联系起来，结合之前报道的研究，可以将多环芳烃空气污染与人类健康影响联系起来。