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The genome of the harpacticoid copepod Tigriopus japonicus: Potential for its use in marine molecular ecotoxicology.
Aquatic Toxicology ( IF 4.1 ) Pub Date : 2020-03-02 , DOI: 10.1016/j.aquatox.2020.105462
Chang-Bum Jeong 1 , Bo-Young Lee 2 , Beom-Soon Choi 3 , Min-Sub Kim 2 , Jun Chul Park 2 , Duck-Hyun Kim 2 , Minghua Wang 4 , Heum Gi Park 5 , Jae-Seong Lee 2
Affiliation  

The copepod Tigriopus japonicus has been widely used as an experimental species in the field of ecotoxicology. We have sequenced and assembled the whole genome of T. japonicus with comparative analysis of gene families that represent detoxification phases in two additional public genomes of Tigriopus spp., namely, T. californicus and T. kingsejongensis. The total length of the T. japonicus assembled genome was 196.6 Mb with an N50 value of 10.65 Mb and consisted of 339 scaffolds and 25,143 annotated genes. The detoxification gene families encoding cytochrome P450s (CYP450s), glutathione S-transferases (GSTs), and ATP-binding cassette (ABC) proteins in Tigriopus spp. have shown species-dependent diversity in several gene sets, suggesting that these genes have undergone a species-specific expansion to increase their fitness to different marine habitats and environmental pressures. Our study will provide a better understanding of the detoxification system in Tigriopus spp. and will contribute to various areas of research, including ecotoxicology.

中文翻译:

类立足类co足类Tigriopus japonicus的基因组:在海洋分子生态毒理学中的应用潜力。

pe足类Tigriopus japonicus已被广泛用作生态毒理学领域的实验物种。我们已经对日本血吸虫的整个基因组进行了测序和组装,并比较了代表Tigriopus spp。的另外两个公共基因组即加利福氏猪笼草和金丝雀属T. kingsejongensis的解毒阶段的基因家族的比较分析。日本血吸虫组装基因组的总长度为196.6 Mb,N50值为10.65 Mb,由339个支架和25,143个带注释的基因组成。Tigriopus spp中编码细胞色素P450(CYP450),谷胱甘肽S-转移酶(GST)和ATP结合盒(ABC)蛋白的解毒基因家族。在几个基因组中显示出物种依赖性的多样性,这表明这些基因已经经历了特定物种的扩展,以增加其适应不同海洋生境和环境压力的能力。我们的研究将使您更好地了解Tigriopus spp的排毒系统。并将为包括生态毒理学在内的各个研究领域做出贡献。
更新日期:2020-03-03
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