This work presents a study, analysis, design, and characterization of a localized surface plasmon resonance (LSPR) based ascorbic acid (AA) sensor with improved sensitivity compared to those already reported. Various multi-tapered (four, five, and eight tapered) optical fiber sensors (OFSs) have been developed and characterized in this study. Along with these, different nanomaterials (NMs), such as gold nanoparticles (AuNPs) and graphene oxide (GO), are immobilized over the bare probe. Further, NMs immobilized probes are functionalized with ascorbate oxidase. The AuNPs are well studied in the past with the variation in size, shape and surface functionalization and have been found to be well-suited NMs for biosensing applications. On the other hand, GO-based material is equally promising in the nanostructure-based optical sensing due to their broad surface area, high electrical conductivity, good chemical stability, and excellent mechanical behavior. The performance parameters of the proposed sensor, such as sensitivity (8.3 nm/mM), correlation correlator (0.9724), and limit of detection (51.94 µM) are greatly improved over the previous designs. A wide range of characterization and validation of NMs immobilized structures are reported here. It indicates a great potential in the practical implementation of LSPR based OFSs for routine diagnostics.

这项工作提出了一种研究，分析，设计和表征基于表面等离振子共振（LSPR）的抗坏血酸（AA）传感器，与已报道的传感器相比，其灵敏度更高。各种多锥度（四个，五个和八个锥形）的光纤传感器（OFS）已被开发和表征。伴随着这些，不同的纳米材料（NMs），例如金纳米颗粒（AuNPs）和氧化石墨烯（GO），被固定在裸探针上。此外，用抗坏血酸氧化酶将固定有NMs的探针功能化。过去，AuNP在尺寸，形状和表面功能化方面存在变化，因此已经得到了很好的研究，并且发现它们非常适合用于生物传感应用的NM。另一方面，基于GO的材料由于其宽的表面积，高的电导率，良好的化学稳定性和优异的机械性能，在基于纳米结构的光学传感中同样有希望。与以前的设计相比，拟议的传感器的性能参数，例如灵敏度（8.3 nm / mM），相关相关器（0.9724）和检测极限（51.94 µM），有了很大的提高。此处报道了NMs固定结构的广泛表征和验证。它表明了在基于LSPR的OFS进行常规诊断的实际实施中的巨大潜力。94 µM）比以前的设计有了很大的改进。此处报道了NMs固定结构的广泛表征和验证。它表明了在基于LSPR的OFS进行常规诊断的实际实施中的巨大潜力。94 µM）比以前的设计有了很大的改进。此处报道了NMs固定结构的广泛表征和验证。这表明在基于LSPR的OFS进行常规诊断的实际实施中具有巨大潜力。