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Appetite for Arginine: Metabolic Control of Macrophage Hunger
Cell Metabolism ( IF 27.7 ) Pub Date : 2020-03-03 , DOI: 10.1016/j.cmet.2020.02.005
Daniel J. Puleston , Erika L. Pearce

Engulfment of dying cells by phagocytes is essential to maintain tissue function and promote injury resolution and repair. This process, termed efferocytosis, requires persistent corpse engulfment and remains a poorly understood mechanism. Here, we preview findings from Yurdagul et al. (2020) that detail how continual efferocytosis is supported by metabolites derived from the dying cell itself.



中文翻译:

精氨酸的食欲:巨噬细胞饥饿的代谢控制。

吞噬细胞吞噬垂死的细胞对于维持组织功能,促进伤口消退和修复至关重要。这个过程称为胞吞,需要持续的尸体吞没,并且仍然是一个鲜为人知的机制。在这里,我们预览了Yurdagul等人的发现。(2020)详细说明了如何从死亡细胞本身衍生的代谢产物支持持续的胞吞作用。

更新日期:2020-03-03
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