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Supramolecular Hyaluronic Assembly with Aggregation-Induced Emission Mediated in Two Stages for Targeting Cell Imaging.
ACS Medicinal Chemistry Letters ( IF 3.5 ) Pub Date : 2020-02-28 , DOI: 10.1021/acsmedchemlett.9b00559
Yang Yang 1 , Ya-Jun Jin 1 , Xin Jia 1 , Shi-Kuo Lu 1 , Ze-Rui Fu 1 , Yu-Xi Liu 1 , Yu Liu 2
Affiliation  

Supramolecular aggregation-induced emission (AIE) has become a research hotspot in cell imaging. Herein, supramolecular assembly with AIE effect was constructed in two stages, where adamantane modified tetraphenylethene self-assembly emitted weak fluorescence, and then after adding β-cyclodextrin modified hyaluronic acid, the formed nanoparticles enhanced AIE fluorescence for targeted cancer cell imaging.

中文翻译:


超分子透明质酸组装与两个阶段介导的聚集诱导发射,用于靶向细胞成像。



超分子聚集诱导发射(AIE)已成为细胞成像的研究热点。本文分两个阶段构建了具有AIE效应的超分子组装体,其中金刚烷修饰的四苯乙烯自组装体发出微弱的荧光,然后在添加β-环糊精修饰的透明质酸后,形成的纳米颗粒增强了AIE荧光,用于靶向癌细胞成像。
更新日期:2020-02-28
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