ABSTRACT Plant microRNAs (miRNAs) are tiny RNAs that are crucial for the biosynthesis of secondary metabolites such as phenylpropanoids because they regulate the activity of key transcription factors and enzymes. Here, we have discussed the significance of miRNAs that target the mRNAs encoding for enzymes and transcription factors in the phenylpropanoid pathway. Genes encoding the miRNAs involved in the synthesis of phenylpropanoids could be considered as potential candidates for metabolic engineering. We have analyzed the construction and potential value of artificial miRNAs (amiRNAs) that could be used for scrutinizing the functional importance of miRNAs in phenylpropanoid biosynthesis and manipulating the pathway for enhancing the production of secondary metabolites.

中文翻译：

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人工微RNA通过苯丙烷途径的代谢工程促进生物分子的高水平生产

摘要 植物微 RNA (miRNA) 是微小的 RNA，对次生代谢物（如苯丙烷）的生物合成至关重要，因为它们调节关键转录因子和酶的活性。在这里，我们讨论了靶向编码苯丙烷途径中酶和转录因子的 mRNA 的 miRNA 的重要性。编码参与苯丙烷合成的 miRNA 的基因可被视为代谢工程的潜在候选者。我们分析了人工 miRNA (amiRNA) 的构建和潜在价值，可用于审查 miRNA 在苯丙烷生物合成中的功能重要性和操纵途径以增强次级代谢物的产生。