Abstract The contents and quantitative methods of fatty acid methyl esters (FAMEs) and polycyclic aromatic hydrocarbons (PAHs) in diesel fuel are strictly regulated for process control and product development. However, extensive manual operations or lengthy processes are required for the existing detection methods. In this study, a high-performance liquid chromatography method with a “selective backflush” strategy was developed for the rapid and simultaneous determination of FAME and PAHs in diesel fuel in one measurement. Compared with the prevailing methods, the proposed method reduced the total measurement time to less than 10 min with satisfactory detection performance, which greatly improved the detection efficiency and saved costs of labor, materials, and time. The feasibility and superiority of this method were demonstrated and the method exhibited great potential for reliable and high-throughput quality control of diesel fuel samples. Furthermore, the selected backflush strategy should expand the realm for developing new chromatographic methods as well as the breadth of applications.

中文翻译：

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采用选择性反吹策略的高效液相色谱法快速同时测定柴油燃料中的脂肪酸甲酯和多环芳烃

摘要 柴油中脂肪酸甲酯（FAMEs）和多环芳烃（PAHs）的含量和定量方法在过程控制和产品开发方面受到严格规定。然而，现有的检测方法需要大量的手动操作或冗长的过程。在本研究中，开发了一种采用“选择性反吹”策略的高效液相色谱方法，用于在一次测量中快速同时测定柴油燃料中的 FAME 和 PAH。与现有方法相比，该方法将总测量时间缩短至10 min以内，检测性能令人满意，大大提高了检测效率，节省了人工、材料和时间成本。证明了该方法的可行性和优越性，该方法在柴油燃料样品的可靠和高通量质量控制方面具有巨大潜力。此外，所选择的反吹策略应扩大开发新色谱方法的领域以及应用的广度。