In this article, we have developed a straightforward, easy and exceedingly competent approach for the synthesis of 5‐phenyl‐5,6‐dihydropyrido[2,3‐d]pyrimidine‐2,4,7(1H,3H,8H)‐triones obtain in superior yields in a sole reaction pace with an air and humidity steady catalyst in water as a green solvent at 100^°C. The present procedure paves the approach for the synthesis of biologically fascinating molecular frameworks and has reward in conditions of little catalyst loading with palpable ambiguous and straightforward‐to‐do reaction circumstances with easy purification process. The used β‐cyclodextrin catalyst was recuperated and repeated several times devoid of noteworthy loss of catalytic activity, which is a crucial parameter of green synthesis.

中文翻译：

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多组分反应和超分子催化剂：水中吡啶并[2,3-d]嘧啶的生态相容性合成的完美协同作用

在本文中，我们开发了一种简单，简单且胜任的方法来合成5-苯基-5,6-二氢吡啶并[2,3 - d ]嘧啶-2,4,7（1 H，3 H，8 H）-三酮与空气和湿气稳定的催化剂在100 ^°C的水中作为绿色溶剂，以单一反应速度即可获得优异的收率C.本方法为生物迷人的分子框架的合成铺平了道路，并且在催化剂负载量少，可触及的模棱两可和直接操作的反应条件下以及易于纯化的条件下获得了回报。回收使用过的β-环糊精催化剂，并重复几次，以确保没有明显的催化活性损失，这是绿色合成的关键参数。