Treatment strategies for asthma are changing dramatically with many novel molecules entering the market, especially within the group of biologicals. Intensive investigations continue to reveal new pathogenetic aspects of the chronic airway inflammation allowing identifying a variety of asthma subendotypes and potential therapeutic targets. Better understanding of the underlying mechanisms as well as contributing factors and triggers allows personalized therapeutic approach respecting individual characteristics of distinct patients.

中文翻译：

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血嗜酸性粒细胞：寻找生物制剂个性化哮喘治疗的圣杯

随着许多新分子进入市场，尤其是在生物制品组中，哮喘的治疗策略正在发生巨大变化。深入的研究继续揭示慢性气道炎症的新发病机制，从而确定各种哮喘亚型和潜在的治疗靶点。更好地了解潜在机制以及促成因素和触发因素，可以制定尊重不同患者个体特征的个性化治疗方法。