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Effect of intraocular anti-VEGF on cystoid macular edema associated with Henoch-Schonlein purpura-a case report.
BMC Ophthalmology ( IF 1.7 ) Pub Date : 2020-02-28 , DOI: 10.1186/s12886-020-01351-x
Dongyan Pan 1 , Xiao Cui 1 , Weiye Zhu 1 , Haifeng Qin 1 , Qing Li 1 , Bing Xu 1 , Jin-Hui Wu 1, 2
Affiliation  

BACKGROUND To report a bilateral cystoid macular edema associated with Henoch-Schonleinpurpura. CASE PRESENTATION A 21-year-old man presented a bilateral, painless, and bilateral blurred vision for 5 weeks with visual acuity (VA) of 6/12 on the right eye and 6/48 on the left. FA and OCT showed bilateral cystoid macular edema, and the fundus photograph showed retinal hemorrhages. Using intravenous dexamethasone could reduce macular edema, but it reoccurred shortly after switching to oral prednisone. Repeated intraocular injection of anti-VEGF in both eyes was performed and VA improved to 6/6 on the right eye and 6/7.5 on the left with the regression of edema after 6 months follow-up. CONCLUSIONS Intraocular anti-VEGF might be an alternative choice to glucocorticoid in cases of bilateral cystoid macular edema associated with Henoch-Schonlein purpura.

中文翻译:

眼内抗VEGF对与过敏性紫癜相关的囊性黄斑水肿的作用-病例报告。

背景技术报道与Henoch-Schonleinpurpura相关的双侧囊样黄斑水肿。病例介绍一名21岁的男子出现双侧,无痛和双侧视力模糊,持续5周,右眼视力(VA)为6/12,左眼视力为6/48。FA和OCT显示双侧囊样黄斑水肿,眼底照片显示视网膜出血。静脉使用地塞米松可以减轻黄斑水肿,但改用口服泼尼松后不久又复发。随访6个月后,双眼重复眼内注射抗-VEGF,右眼VA提高至6/6,左眼VA提高至6 / 7.5,水肿消退。
更新日期:2020-03-02
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