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A first step towards building spectral libraries as complementary tools for snake venom proteome/peptidome studies
Comparative Biochemistry and Physiology D: Genomics & Proteomics ( IF 2.2 ) Pub Date : 2019-05-31 , DOI: 10.1016/j.cbd.2019.100599 André Zelanis , Débora A. Silva , Eduardo S. Kitano , Tarcísio Liberato , Isabella Fukushima , Solange M.T. Serrano , Alexandre K. Tashima
中文翻译:
建立光谱库作为蛇毒蛋白质组/肽组研究的辅助工具的第一步
更新日期:2019-05-31
Comparative Biochemistry and Physiology D: Genomics & Proteomics ( IF 2.2 ) Pub Date : 2019-05-31 , DOI: 10.1016/j.cbd.2019.100599 André Zelanis , Débora A. Silva , Eduardo S. Kitano , Tarcísio Liberato , Isabella Fukushima , Solange M.T. Serrano , Alexandre K. Tashima
Snake venoms are complex mixtures of a large number of distinct proteins and peptides with biological activity. Peptide spectral libraries are compilations of previously identified MS/MS spectra obtained from proteomics experiments. Here we present the generation and use of a Venom Peptidome and a Venom Proteome spectral library for the analysis of venom proteomes and peptidomes from distinct snake species.
中文翻译:
建立光谱库作为蛇毒蛋白质组/肽组研究的辅助工具的第一步
蛇毒是具有生物学活性的大量不同蛋白质和肽的复杂混合物。肽谱库是从蛋白质组学实验中获得的先前鉴定的MS / MS谱图的汇编。在这里,我们介绍毒液肽组和毒液蛋白质组谱库的生成和使用,以分析来自不同蛇种的毒液蛋白质组和肽组。