A literature survey covering the report on Pirkle-type chiral stationary phases (CSPs) from January 2000 to March 2017 is presented in this review. More than 200 CSPs comprising small molecules as chiral selectors covalently bound to the chromatographic support have been reported in this period. The chemical nature of these new chiral selectors, new insights into the development strategies and their applications in liquid chromatography were emphasized.

中文翻译：

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基于小分子的手性固定相：最近17年的更新。

本文综述了2000年1月至2017年3月Pirkle型手性固定相（CSP）报告的文献调查。在此期间，已经报道了200多种包含小分子作为手性选择剂的CSP，它们与色谱支持物共价结合。强调了这些新型手性选择剂的化学性质，对开发策略的新见解及其在液相色谱中的应用。