Efficient enantioselective separation is a challenging task due to the identical physical and chemical properties of enantiomers. Functionalized magnetic nanomaterials modified with chiral ligands on their surface possess both magnetic property and chiral recognition ability, and have demonstrated great potential in chiral discrimination. This review summarizes the applications of magnetic nanomaterials modified with various chiral selectors (e.g., β-cyclodextrins, polymers, proteins, amino acids and cellulose) in enantioselective separation. After proper preparation and modification, these functionalized magnetic nanomaterials are effective for enantioseparation. Therefore, enantioseparations based on functionalized magnetic nanomaterials are convenient, economical and effective.

由于对映异构体的物理和化学性质相同，有效的对映选择性分离是一项艰巨的任务。在其表面上被手性配体修饰的功能化磁性纳米材料既具有磁性，又具有手性识别能力，并且在手性识别方面显示出巨大的潜力。这篇综述总结了用各种手性选择剂（例如，β-环糊精，聚合物，蛋白质，氨基酸和纤维素）修饰的磁性纳米材料在对映选择性分离中的应用。经过适当的制备和修饰后，这些功能化的磁性纳米材料可有效用于对映体分离。因此，基于功能化磁性纳米材料的对映异构体是方便，经济和有效的。