The increased complexity of sample matrices resulted in the requirement of specific and sensitive molecular recognition systems. Although molecular imprinting is an old idea, its potential as molecular recognition tool in analytical chemistry has been revived in recent times. This review intended to comprehensively discuss and evaluate the recent progress in the applications of molecularly imprinted polymers (MIPs) in analytical chemistry. A concise introduction for new readers in the field is followed by the comprehensive critical review of these developments in MIP technology and their applications in analytical chemistry. This review is divided into three sections namely, extraction, sensors and chromatography. The three sections are further separated into several sub-sections. The applications related to compound extraction are subdivided into extraction of toxins and bioactive compound extraction. MIPs as sensors are subdivided into luminescence probes, surface plasmon resonance (SPR) sensors, quartz crystal microbalance (QCM) and electrochemical sensors. Finally, the MIP applications as stationary phase for chromatography are elaborated. This section is subdivided into HPLC and capillary electrochromatography (CEC). The significant aspects of applications of the molecular imprinting polymers in analytical chemistry are evaluated focusing majorly on literature appeared in last five years.

样品基质复杂性的增加导致需要特定而敏感的分子识别系统。尽管分子烙印是一个古老的想法，但其在分析化学中作为分子识别工具的潜力已在最近恢复。这篇综述旨在全面讨论和评估分子印迹聚合物（MIP）在分析化学中的应用的最新进展。在为该领域的新读者提供简要介绍之后，将对MIP技术的发展及其在分析化学中的应用进行全面的批判性评论。这篇综述分为三个部分，即提取，传感器和色谱。这三个部分进一步分为几个子部分。与化合物提取有关的应用细分为毒素提取和生物活性化合物提取。作为传感器的MIP分为发光探针，表面等离子体共振（SPR）传感器，石英微天平（QCM）和电化学传感器。最后，阐述了MIP作为色谱固定相的应用。本节分为HPLC和毛细管电色谱（CEC）。对分子印迹聚合物在分析化学中的重要应用方面进行了评估，主要侧重于近五年来出现的文献。阐述了MIP作为色谱固定相的应用。本节分为HPLC和毛细管电色谱（CEC）。对分子印迹聚合物在分析化学中的重要应用方面进行了评估，主要侧重于近五年来出现的文献。阐述了MIP作为色谱固定相的应用。本节分为HPLC和毛细管电色谱（CEC）。对分子印迹聚合物在分析化学中的重要应用方面进行了评估，主要侧重于近五年来出现的文献。