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Preparation and Characterization of Nanocomposite Scaffolds Based on Polycaprolactone-Polyethylene Glycol/Methylene Diphenyl Diisocyanate/Diethylene Glycol and Nano-Bioactive Glass
Journal of Macromolecular Science Part B-Physics ( IF 1.2 ) Pub Date : 2019-03-21 , DOI: 10.1080/00222348.2019.1578529
Xiaofei Li 1 , Jianjun Fang 1, 2 , Hua Yan 1 , Wenjuan Liu 2 , Yunhui Zhao 1 , Tianlong Huang 3 , Jiale Cui 1 , Yun Yang 1 , Zhihua Zhou 1, 2, 4
Affiliation  

Designing and fabricating nanocomposite scaffolds based on biodegradable polymers and bioactive materials are an important topic in the area of bone regeneration. A novel nanocomposite scaffold composed of polyurethane (BPU) and nano-bioactive glass (NBAG) was prepared. The effects of the NBAG content on the properties of the BPU/NBAG composite scaffolds, including the morphologies, porosity and compressive strength, were investigated. The BPU/NBAG composite scaffolds showed an interconnected pore structure with the pore size ranging from 50 to 500 μm for all samples. The porosity percent and swelling ability decreased with increasing NBAG content; however, the compressive strength was enhanced.



中文翻译:

基于聚己内酯-聚乙二醇/亚甲基二苯基二异氰酸酯/二乙二醇和纳米生物活性玻璃的纳米复合支架的制备与表征

基于可生物降解的聚合物和生物活性材料的纳米复合支架的设计和制造是骨再生领域的重要课题。制备了由聚氨酯(BPU)和纳米生物活性玻璃(NBAG)组成的新型纳米复合支架。研究了NBAG含量对BPU / NBAG复合支架性能的影响,包括形态,孔隙率和抗压强度。BPU / NBAG复合支架显示出相互连接的孔结构,所有样品的孔尺寸在50至500μm之间。孔隙率和溶胀能力随NBAG含量的增加而降低。但是,抗压强度提高了。

更新日期:2019-03-21
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