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The association between changes in muscle mass and quality of life in patients with metastatic colorectal cancer.
Journal of Cachexia, Sarcopenia and Muscle ( IF 9.4 ) Pub Date : 2020-02-27 , DOI: 10.1002/jcsm.12562 Jeroen W G Derksen 1, 2 , Sophie A Kurk 1, 2 , Petra H M Peeters 2 , Bram Dorresteijn 3 , Marion Jourdan 3 , Ankie M T van der Velden 4 , Peter Nieboer 5 , Robert S de Jong 6 , Aafke H Honkoop 7 , Cornelis J A Punt 8 , Miriam Koopman 1 , Anne M May 2
Journal of Cachexia, Sarcopenia and Muscle ( IF 9.4 ) Pub Date : 2020-02-27 , DOI: 10.1002/jcsm.12562 Jeroen W G Derksen 1, 2 , Sophie A Kurk 1, 2 , Petra H M Peeters 2 , Bram Dorresteijn 3 , Marion Jourdan 3 , Ankie M T van der Velden 4 , Peter Nieboer 5 , Robert S de Jong 6 , Aafke H Honkoop 7 , Cornelis J A Punt 8 , Miriam Koopman 1 , Anne M May 2
Affiliation
Skeletal muscle mass (SMM) loss is common in metastatic colorectal cancer (mCRC) patients and associated with poor clinical outcomes, including increased treatment‐related toxicities and reduced survival. Muscle loss may contribute to reduced health‐related quality of life (HRQoL), including fatigue. Our aim was to study associations between changes in SMM and concomitant changes in patient‐reported HRQoL.
中文翻译：
转移性结直肠癌患者肌肉质量变化与生活质量之间的关联。
骨骼肌质量 (SMM) 损失在转移性结直肠癌 (mCRC) 患者中很常见，并且与较差的临床结果相关，包括治疗相关毒性增加和存活率降低。肌肉损失可能导致健康相关生活质量 (HRQoL) 降低，包括疲劳。我们的目的是研究 SMM 的变化与患者报告的 HRQoL 的伴随变化之间的关联。
更新日期：2020-02-27
中文翻译：
转移性结直肠癌患者肌肉质量变化与生活质量之间的关联。
骨骼肌质量 (SMM) 损失在转移性结直肠癌 (mCRC) 患者中很常见，并且与较差的临床结果相关，包括治疗相关毒性增加和存活率降低。肌肉损失可能导致健康相关生活质量 (HRQoL) 降低，包括疲劳。我们的目的是研究 SMM 的变化与患者报告的 HRQoL 的伴随变化之间的关联。
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