Recent findings demonstrate that pharmacological cyclin-dependent kinase 7 (CDK7) inhibitors can evoke anticancer immunity upon genomic destabilization of neoplastic cells. Besides adding CDK7 to the expanding list of cell cycle proteins that impinge on immune regulation, these results support the value of aggravating genomic instability in cancer cells to enable immunological disease control.

中文翻译：

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CDK7抑制剂的癌症免疫疗法。

最近的发现表明，药理细胞周期蛋白依赖性激酶7（CDK7）抑制剂可在肿瘤细胞基因组不稳定后唤起抗癌免疫力。除了将CDK7添加到影响免疫调节的不断增加的细胞周期蛋白列表之外，这些结果还支持加剧癌细胞基因组不稳定性以实现免疫疾病控制的价值。