Transgender individuals represent a small, albeit growing, patient population that is encountered more frequently in clinical care due to improved insurance coverage and increasing awareness. Gender-affirming treatments, including both gender-affirming hormone therapy and gender-affirming surgery, pose significant risks to fertility potential and outcomes, ranging from potentially impaired fertility rates to full elimination of reproductive potential depending on the type of treatment pursued. However, there are relatively limited data specific to fertility preservation for transgender individuals. Current approaches to treatment are extrapolated from options for fertility preservation after oncologic diagnoses. In this review, we aim to summarize current clinical approaches, fertility preservation options, and patient experiences in fertility preservation for transgender individuals. Several forms of fertility preservation options are available depending on the pubertal status of a transgender individual. Despite the multiple options for fertility preservation, major barriers exist to patient care and there are reports of mixed patient experiences. Further awareness of this clinical situation and understanding of these processes will allow for comprehensive and specialized care for transgender individuals who may otherwise miss opportunities for adequate counseling or treatment options regarding fertility preservation.

中文翻译：

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变性者的生育保护：回顾。

跨性别者代表的人群虽然很小，但仍在增长，由于保险覆盖率的提高和认知度的提高，其在临床护理中遇到的频率更高。包括性别确认激素疗法和性别确认手术在内的性别确认疗法对生育潜力和结局构成重大风险，其范围从潜在的生育率降低到完全消除生殖潜力，取决于所追求的治疗类型。但是，针对跨性别者的生育能力保留的数据相对有限。从肿瘤诊断后保留生育能力的选择中推断出当前的治疗方法。在这篇评论中，我们旨在总结当前的临床方法，生育力保留方案，以及为变性者保留生育能力的患者经验。根据跨性别者的青春期状态，可以使用多种形式的生育保护方法。尽管保留生育能力有多种选择，但患者护理仍然存在主要障碍，并且有患者经历混合的报道。对这种临床情况的进一步了解和对这些过程的了解将为跨性别者提供全面和专门的护理，否则他们可能会错过有关生育保护的充分咨询或治疗选择的机会。病人护理存在主要障碍，并且有病人经历混合的报道。对这种临床情况的进一步了解和对这些过程的了解将为跨性别者提供全面和专门的护理，否则他们可能会错过有关生育保护的充分咨询或治疗选择的机会。病人护理存在主要障碍，并且有病人经历混合的报道。对这种临床情况的进一步了解和对这些过程的了解将为跨性别者提供全面和专门的护理，否则他们可能会错过有关生育保护的充分咨询或治疗选择的机会。