AIM In 1999, a cooperative tripartite cancer research and training agreement was signed between Ireland (IE), Northern Ireland (NI) and the United States (US) National Cancer Institute, giving rise to the All-Ireland Cancer Consortium (AICC). We wished to consider if AICC increased the amount/impact of cancer research on the island of Ireland and what effect this enhanced research activity had on cancer services and cancer outcomes. METHODS As comparator, we chose the city regions of Copenhagen and Lund & Malmö, whose physical connection was greatly improved following construction of bridges between Denmark and Sweden around the time AICC was established. We analysed cancer research outputs from all four geographical regions in the Web of Science (1988-2017), with a particular focus on citations and journal impact factors. We evaluated disability-adjusted life years (DALYs) as an indicator of change in health status. RESULTS Research outputs increased in all four regions, but more in IE/NI than in the Scandinavian cities, while collaboration between IE and NI and both the US and the Rest of Europe increased even more substantially. Citation scores also showed a greater improvement for IE and NI. Journal citation impact factors indicated that IE/NI papers were increasingly being published in more highly cited journals. Research-enabled cancer service provision improved on the island of Ireland, with concomitant increases in cancer survival. CONCLUSION The AICC collaborative agreement delivered significant additionality on the island of Ireland, promoting transnational cooperation, enhancing cancer research activity, and underpinning improved cancer services and better cancer outcomes.

中文翻译：

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《耶稣受难日协议》和爱尔兰岛的癌症研究：三方癌症研究伙伴关系的影响的证据。

目的1999年，爱尔兰（IE），北爱尔兰（NI）和美国（US）国家癌症研究所签署了一项合作的三方癌症研究和培训协议，从而成立了全爱尔兰癌症联盟（AICC）。我们希望考虑AICC是否会增加爱尔兰岛上癌症研究的数量/影响，以及这种增强的研究活动对癌症服务和癌症结局有何影响。方法作为比较者，我们选择了哥本哈根市和隆德和马尔默市，在AICC建立之初，随着丹麦和瑞典之间桥梁的建造，其物理联系得到了极大改善。我们分析了Web of Science（1988-2017）中所有四个地理区域的癌症研究成果，特别关注引文和期刊影响因子。我们评估了残疾调整生命年（DALYs）作为健康状况变化的指标。结果四个地区的研究产出均增加了，但IE / NI的增长超过了斯堪的纳维亚城市，而IE和NI以及美国和欧洲其他地区之间的合作则大大增加。引用分数也显示IE和NI的改善更大。期刊引文影响因素表明，IE / NI论文正越来越多地在引用率更高的期刊上发表。爱尔兰岛上以研究为基础的癌症服务提供得到改善，伴随着癌症生存期的增加。结论AICC合作协议在爱尔兰岛上带来了重大意义，促进了跨国合作，增强了癌症研究活动，