NoncoRNA (http://www.ncdtcdb.cn:8080/NoncoRNA/) is a manually curated database of experimentally supported non-coding RNAs (ncRNAs) and drug target associations that aim to potentially provide a high-quality data resource for exploring drug sensitivity/resistance-related ncRNAs in various human cancers. ncRNA are RNA molecular that do not encode proteins, but are involved in gene regulation and cellular functions in variety of human diseases, including neurodegenerative diseases and cancers. Here, we developed NoncoRNA which contained 8233 entries between 5568 ncRNAs and 154 drugs in 134 cancers. Each entry in the NoncoRNA contains detailed information on the ncRNAs, drugs, and cancers, the ncRNA expression pattern and experimental detection techniques, drug response and other targets, literature references, and other information. NoncoRNA offers a user-friendly, open access web interface to easily browse, search, and download data. NoncoRNA also provides a submission page for researchers to submit newly validated ncRNA-drug-cancer associations. NoncoRNA might serve as an immeasurable resource for understanding the roles of ncRNAs in cancer therapy.

中文翻译：

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NoncoRNA：癌症中实验支持的非编码RNA和药物靶标的数据库。

NoncoRNA（http://www.ncdtcdb.cn:8080/NoncoRNA/）是人工支持的数据库，其中包含实验支持的非编码RNA（ncRNA）和药物靶标关联，旨在潜在地提供用于探索药物的高质量数据资源各种人类癌症中与敏感性/耐药性相关的ncRNA。ncRNA是不编码蛋白质的RNA分子，但参与多种人类疾病（包括神经退行性疾病和癌症）的基因调控和细胞功能。在这里，我们开发了NoncoRNA，它包含134种癌症中的5568个ncRNA和154种药物之间的8233个条目。NoncoRNA中的每个条目都包含有关ncRNA，药物和癌症，ncRNA表达模式和实验检测技术，药物反应和其他靶标，文献参考以及其他信息的详细信息。NoncoRNA提供了一个用户友好的开放访问Web界面，可以轻松浏览，搜索和下载数据。NoncoRNA还提供了一个提交页面，供研究人员提交新验证的ncRNA-药物-癌症关联。NoncoRNA可能是了解ncRNA在癌症治疗中作用的不可估量的资源。