The metal-catalyzed processes are ubiquitous in the modern organic synthesis toolbox. However, a continuous challenge has been related to the design of reactions from a sustainable viewpoint (e.g., easy recovery of the catalyst, ability to perform sequential steps in high yields, avoidance of high amounts of organic solvents). Supported nanocatalysts have prompted special interest because of the synergy involving eletronic and surface effects which can play key roles towards more sustainable processes. In this article, we comprehensively summarize the latest progress in cross-coupling reactions involving supported metal nanoparticles. A background to mechanisms and industrial application will also be presented.

在现代有机合成工具箱中，金属催化的方法无处不在。然而，从可持续的角度来看，与反应的设计有关的挑战是连续的（例如，催化剂的容易回收，以高收率进行连续步骤的能力，避免大量的有机溶剂）。负载型纳米催化剂引起了人们的特别关注，因为涉及电子和表面效应的协同作用可以在更可持续的过程中发挥关键作用。在本文中，我们全面总结了涉及负载型金属纳米颗粒的交叉偶联反应的最新进展。还将介绍机制和工业应用的背景。