Bionanomaterial-based electrochemical biosensing platforms for biomedical applications,Analytical Methods

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Bionanomaterial-based electrochemical biosensing platforms for biomedical applications
Analytical Methods ( IF 2.7 ) Pub Date : 2020-02-27 , DOI: 10.1039/d0ay00171f
Govindhan Maduraiveeran _{1,

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Affiliation

In recent years, bionanomaterial-based electrochemical biosensor platforms have received much attention for the detection of various emerging biomarkers in the clinical, pharmaceutical, and biological fields. The integration of electrochemical systems with biomaterials, including proteins/enzymes, nucleic acids, and biopolymers, provides rapid, sensitive and selective detection of biomarkers. This review discusses the development of biomaterial-derived electrochemical sensors and biosensor platforms for the next generation of medical diagnosis and real-time monitoring of the clinical status of patients at various levels. The complete utilization of various bionanomaterials and their nanocomposites in the design of high-performance electrochemical biosensor platforms for the sensitive and selective detection of emergent biomarkers will be described. Moreover, the prominent opportunities for designing biomaterials and analytical strategies to improve the performance of biosensors via multi-label intensification integrated with high volumes of capture molecules on material surfaces for further advances in biomedical fields will be discussed.

中文翻译：

用于生物医学的基于生物材料的电化学生物传感平台

近年来，基于生物纳米材料的电化学生物传感器平台在临床，制药和生物领域中用于检测各种新兴生物标志物已引起了广泛关注。电化学系统与生物材料（包括蛋白质/酶，核酸和生物聚合物）的集成，提供了对生物标志物的快速，灵敏和选择性检测。这篇综述讨论了生物材料衍生的电化学传感器和生物传感器平台的发展，用于下一代医学诊断和实时监测各级患者的临床状况。将描述在高性能电化学生物传感器平台的设计中对各种生物纳米材料及其纳米复合材料的完全利用，以对出现的生物标记物进行灵敏和选择性的检测。本文将讨论通过多标记增强与材料表面上大量捕获分子整合在一起，以进一步发展生物医学领域。

更新日期：2020-02-27

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