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Effect of fennel supplementation along with high-protein, low-carbohydrate weight-loss diet on insulin resistance and percentage of fat and muscle mass in overweight/obese women with polycystic ovary syndrome
Journal of Functional Foods ( IF 5.6 ) Pub Date : 2020-02-26 , DOI: 10.1016/j.jff.2020.103848
Elham Hosseini Marnani , Akram Ghadiri-Anari , Nahid Ramezani-Jolfaie , Mohammad Mohammadi , Nooshin abdollahi , Seyedeh Mahdieh Namayandeh , Hassan Mozaffari-Khosravi , Amin Salehi-Abargouei , Azadeh Nadjarzadeh

The aim of this study was investigated the effects of fennel supplementation with energy-restricted diets on body fat and muscle percentage and insulin resistance in women with PCOS. Sixty-four overweight/obese women with PCOS were randomly allocated to 4 groups for 12 weeks as follows: (1) standard diet + fennel (SDF), (2) high-protein, low-carbohydrate diet supplemented with fennel (HPF), (3) standard diet + placebo (SDP), and (4) high-protein, low-carbohydrate diet + placebo (HPP). After 12 weeks of intervention, there were significant changes in the percentage of body fat and muscle in all groups. Decreasing in fasting insulin was −4.12 micIU/ml (P = 0.01) for HPF and −4.5 micIU/ml (P = 0.03) for SDP groups. In addition, HOMA-IR significantly decreased in HPF (P = 0.02) and SDP (P = 0.02) groups. Energy-restricted diets independent of dietary composition improved the body fat and muscle percentage and insulin resistance indices in women with PCOS. High-protein diet and fennel compared with standard diet and placebo had no significant effect on insulin resistance, body fat and muscle.



中文翻译:

补充茴香以及高蛋白,低碳水化合物的减肥饮食对多囊卵巢综合征超重/肥胖妇女胰岛素抵抗以及脂肪和肌肉质量百分比的影响

这项研究的目的是调查补充能量受限饮食的茴香对PCOS妇女体内脂肪和肌肉百分比以及胰岛素抵抗的影响。将64名PCOS超重/肥胖妇女随机分为4组,每组12周,具体方法如下:(1)标准饮食+茴香(SDF),(2)补充茴香(HPF)的高蛋白,低碳水化合物饮食, (3)标准饮食+安慰剂(SDP),以及(4)高蛋白,低碳水化合物饮食+安慰剂(HPP)。干预12周后,所有组的体内脂肪和肌肉百分比均发生了显着变化。HPF空腹胰岛素减少为-4.12 micIU / ml(P = 0.01),SDP组减少为-4.5 micIU / ml(P = 0.03)。此外,HPF(P = 0.02)和SDP(P = 0.02)组的HOMA-IR显着降低。与饮食组成无关的能量受限饮食可改善患有PCOS的女性的体内脂肪和肌肉百分比以及胰岛素抵抗指数。与标准饮食和安慰剂相比,高蛋白饮食和茴香对胰岛素抵抗,体脂和肌肉没有显着影响。

更新日期:2020-02-27
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