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Arthritis & Rheumatology ( IF 11.4 ) Pub Date : 2020-02-26 , DOI: 10.1002/art.41237
Minzhi Yu 1 , Sang Y Kim 1 , Emily E Morin 1 , Anna Schwendeman 1
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We thank Dr. Vuilleumier for his interest in our review paper on high-density lipoproteins (HDLs) in systemic lupus erythematosus (SLE) and his comments on anti-apolipoprotein A-1 (apoA-1) autoantibodies. Dr. Vuilleumier raises an important point that the prevalence of high anti-apoA-1 IgG levels is not specific to SLE, which we fully agree with. The prevalence of anti-apoA-1 autoantibodies in different disease settings has been summarized in Table 1. Inconsistent results could be attributed to the assay-to-assay differences introduced by different enzyme-linked immunosorbent assay (ELISA) assays and different positivity cut-off values used.

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我们感谢 Vuilleumier 博士对我们关于系统性红斑狼疮 (SLE) 高密度脂蛋白 (HDL) 的综述论文的兴趣以及他对抗载脂蛋白 A-1 (apoA-1) 自身抗体的评论。 Vuilleumier 博士提出了一个重要观点,即高抗 apoA-1 IgG 水平的流行并不是 SLE 所特有的,我们完全同意这一点。表 1 总结了不同疾病环境中抗 apoA-1 自身抗体的流行情况。结果不一致可能是由于不同酶联免疫吸附测定 (ELISA) 测定和不同的阳性截断引入的测定间差异所致。使用关闭值。
更新日期:2020-02-26
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