Membrane emulsification has the potential to revolutionize the energy‐efficient production of uniform emulsions and dispersions, relevant to diverse fields from pharmaceutical active ingredient controlled release particles to Fast Moving Consumer Goods. A novel highly robust single‐pass continuous phase crossflow system has been developed providing dispersed phase concentrations up to 40% vol/vol and dispersed phase fluxes up to 5,730 L m⁻² hr⁻¹, from a single 100 mm long membrane tube. Extensive results of two oil‐in‐water systems (vegetable oil and PolyCaproLactone dissolved in DiChloroMethane) and one water‐in‐oil system (sodium silicate solution) are reported, using hydrophilic and hydrophobic membranes respectively. Mathematical models are validated enabling comprehensive engineering analysis of processes including predicted droplet size, membrane pressure drops, and energy requirement for dispersion production. Surfactant depletion, pore utilization, and droplet interaction at the membrane surface were investigated to provide a comprehensive analysis of the capabilities of novel annular‐flow membrane emulsification for high throughput emulsion generation.

中文翻译：

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使用单程环形流错流膜进行高通量膜乳化

膜乳化有可能彻底改变均匀乳液和分散体的节能生产方式，涉及从药物活性成分控释颗粒到快速消费品的各个领域。已开发出一种新型的高度耐用的单程连续相错流系统，可提供高达40％vol / vol的分散相浓度和高达5,730 L m ^-2 hr ^-1的分散相通量从单个100毫米长的膜管中取出。分别使用亲水性和疏水性膜报道了两种水包油系统（植物油和溶于二氯甲烷中的聚己内酯）和一种油包水系统（硅酸钠溶液）的广泛结果。通过数学模型验证，可以对工艺进行全面的工程分析，包括预测的液滴尺寸，膜压降和分散液生产所需的能量。研究了表面活性剂的消耗，孔隙利用和膜表面的液滴相互作用，以全面分析新型环流膜乳化的高通量乳液生成能力。