Abstract Amphiphilic polymers (APs) characterized with excellent water solubility, biodegradability, biocompatibility, and low toxicity have become popular materials for biological sensing and imaging in the recent years. Among the several sensing and imaging techniques, fluorescence-based methods show distinct advantages and present unique opportunities to address challenges afforded by other techniques. This review covers five different types of APs (amphiphilic-conjugated polymers, amphiphilic polysaccharides, amphiphilic molecularly imprinted polymers, amphiphilic block copolymers, and amphiphilic polymeric nanoparticles) and their application for fluorescence spectroscopic sensing and imaging, in particular how techniques have been progressed over recent years. Afterwards, the applications of APs in the diagnosis and treatment of diseases, water safety and environmental monitoring has been discussed.

中文翻译：

---

用于传感和成像的基于两亲聚合物的荧光光谱技术的最新进展

摘要 两亲性聚合物 (APs) 具有优异的水溶性、生物降解性、生物相容性和低毒性，近年来已成为生物传感和成像的热门材料。在几种传感和成像技术中，基于荧光的方法显示出明显的优势，并为解决其他技术带来的挑战提供了独特的机会。本综述涵盖了五种不同类型的 AP（两亲共轭聚合物、两亲多糖、两亲分子印迹聚合物、两亲嵌段共聚物和两亲聚合物纳米粒子）及其在荧光光谱传感和成像中的应用，特别是近年来技术的进展情况年。随后，APs在疾病诊断和治疗中的应用，