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Isolated nail lichen planus: An expert consensus on treatment of the classical form.
Journal of the American Academy of Dermatology ( IF 12.8 ) Pub Date : 2020-02-26 , DOI: 10.1016/j.jaad.2020.02.056
Matilde Iorizzo 1 , Antonella Tosti 2 , Michela Starace 3 , Robert Baran 4 , C Ralph Daniel 5 , Nilton Di Chiacchio 6 , Sophie Goettmann 7 , Chander Grover 8 , Eckart Haneke 9 , Shari R Lipner 10 , Phoebe Rich 11 , Bertrand Richert 12 , Dimitris Rigopoulos 13 , Adam I Rubin 14 , Martin Zaiac 15 , Bianca Maria Piraccini 3
Affiliation  

Lichen planus is a benign inflammatory disorder of unknown etiology that may affect the skin, mucosae, scalp, and nails. When the nails are affected, it may lead to permanent destruction with severe functional and psychosocial consequences. Therefore, prompt diagnosis and early treatment are essential, even in mild cases. There are currently no guidelines for the management of nail lichen planus and the published literature on treatment is limited. The aim of this review is to provide practical management recommendations for the classical form of nail lichen planus, especially when restricted to the nails. Topical treatment has poor short-term efficacy and may cause long-term side effects. Instead, intralesional and intramuscular triamcinolone acetonide should be considered first-line therapies. Oral retinoids are second-line choices, and immunosuppressive agents may also be considered.



中文翻译:

孤立的指甲扁平苔藓:治疗经典形式的专家共识。

扁平苔藓是一种病因不明的良性炎性疾病,可能会影响皮肤,粘膜,头皮和指甲。当指甲受到影响时,可能会导致永久性破坏,并带来严重的功能和社会心理后果。因此,即使在轻度病例中,及时诊断和早期治疗也是必不可少的。目前尚无治疗指甲扁平苔藓的指南,有关治疗的公开文献有限。这篇综述的目的是为指甲扁平苔藓的经典形式提供实用的管理建议,尤其是限于指甲时。局部治疗短期疗效较差,可能引起长期副作用。相反,应将病灶内和肌内注射曲安奈德作为一线治疗方法。口服类维生素A是第二线的选择,

更新日期:2020-02-26
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