How many cells are enough for single-cell infrared spectroscopy?,Chemical Communications

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How many cells are enough for single-cell infrared spectroscopy?
Chemical Communications ( IF 4.3 ) Pub Date : 2020/02/26 , DOI: 10.1039/d0cc00067a
Yadi Wang ₁ , Wentao Dai , Yue Wang , Jixiang Liu , Zhixiao Liu , Yuanyuan Li , Xueling Li , Jun Hu , Junhong Lü

Affiliation

The influence of cell number on spectral variability among two different cell types and two states was quantitatively analyzed and evaluated by calculating the similarity distance of the single-cell spectral data obtained from synchrotron infrared microspectroscopy. We found that at least 15 cells are required to achieve robust results with 95% confidence.

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