Abstract In this study, a high shear-high pressure homogenization bonding technology, natural surfactant glycyrrhizic acid (GA), synthetic nonionic surfactant Tween 80 (T80) and synthetic ionic surfactant (SDS) were used to prepare the nanoemulsion of hesperidin (HDN-NE), and their solubilization, forming and stabilization mechanism were studied respectively. From the perspective of solubilization, the order of molar solublization ratio (MSR) was GA > T80 > SDS. From forming, there were a uniform appearance, smaller particle size (

中文翻译：

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表面活性剂增溶、形成和稳定橙皮苷纳米乳剂的比较

摘要 本研究采用高剪切-高压均质粘合技术、天然表面活性剂甘草酸(GA)、合成非离子表面活性剂吐温80(T80)和合成离子表面活性剂(SDS)制备橙皮苷纳米乳(HDN-NE)。 )，并分别研究了它们的增溶、形成和稳定机制。从增溶的角度来看，摩尔增溶比（MSR）的顺序是GA>T80>SDS。成型后外观均匀，粒径较小（