An efficient and simple synthesis of substituted 1H-pyrrole-3-carbonitriles was developed. This reaction is a palladium(II)-catalyzed cascade of C(sp)–C(sp²) coupling followed by intramolecular C–N bond formation. The method can tolerate various substrates with satisfactory yields. Its ligand-free conditions and high efficiency make this method particularly attractive.

中文翻译：

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通过无配体钯（II）催化的C（sp）–C（sp2）偶联反应取代1H-吡咯-3-腈的级联反应

开发了一种有效和简单的取代1 H-吡咯-3-腈的合成方法。此反应是钯（II）催化的C（sp）–C（sp ²）偶联级联反应，随后形成分子内C–N键。该方法可以以令人满意的产率耐受各种底物。它的无配体条件和高效率使该方法特别有吸引力。