Continuous-Flow Dynamic Kinetic Resolution of Racemic Alcohols by Lipase-Oxovanadium Cocatalysis,European Journal of Organic Chemistry

当前位置： X-MOL 学术 › Eur. J. Org. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Continuous-Flow Dynamic Kinetic Resolution of Racemic Alcohols by Lipase-Oxovanadium Cocatalysis
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2020-03-17 , DOI: 10.1002/ejoc.202000186
Koichi Higashio ₁ , Satoko Katsuragi ₁ , Dhiman Kundu ₁ , Niklas Adebar ₂ , Carmen Plass ₂ , Franziska Kühn ₂ , Harald Gröger ₂ , Shuji Akai ₁

Affiliation

A continuous-flow dynamic kinetic resolution of racemic secondary alcohols was carried out using a single column reactor packed with a mixture of immobilized lipase and an immobilized oxovanadium species, VMPS4. As a result, optically pure esters were produced in 88–92 % yields. Problems encountered in this study were overcome by using fillers that efficiently

中文翻译：