The severity of motor symptoms in Parkinson's disease (PD) does not always correlate with the degree of nigral dopaminergic neuronal loss. Individuals with greater motor reserve may have milder motor signs than their striatal dopamine loss. In this study, we explored the functional brain network associated with motor reserve in early‐stage PD.

中文翻译：

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识别早期帕金森病运动储备的功能性脑网络

帕金森病 (PD) 运动症状的严重程度并不总是与黑质多巴胺能神经元丢失的程度相关。与纹状体多巴胺损失相比，具有更大运动储备的个体可能具有更轻微的运动症状。在这项研究中，我们探索了与早期 PD 运动储备相关的功能性大脑网络。