Contrast‐Enhanced Ultrasound Imaging: Gas‐Generating, pH‐Responsive Calcium Carbonate Hybrid Particles with Biomimetic Coating for Contrast‐Enhanced Ultrasound Imaging (Part. Part. Syst. Charact. 2/2020),Particle & Particle Systems Characterization

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Contrast‐Enhanced Ultrasound Imaging: Gas‐Generating, pH‐Responsive Calcium Carbonate Hybrid Particles with Biomimetic Coating for Contrast‐Enhanced Ultrasound Imaging (Part. Part. Syst. Charact. 2/2020)
Particle & Particle Systems Characterization ( IF 2.7 ) Pub Date : 2020-02-20 , DOI: 10.1002/ppsc.202070005
Mark Louis P. Vidallon ₁ , Alon M. Douek ₂ , Adam Quek ₃ , Heather McLiesh ₄ , Jan Kaslin ₂ , Rico F. Tabor ₁ , Alexis I. Bishop ₅ , Boon Mian Teo ₁

Affiliation

In article number 1900471, Boon Mian Teo and co‐workers present a polydopamine/bovine serum albumin/calcium carbonate (PDA/BSA/CaCO₃) hybrid particle system with a biomimetic red blood cell (RBC) membrane coating. This particle system combines the capability of the RBC membrane to modulate protein corona formation with the pH‐sensitivity of CaCO₃, producing hyper‐echogenic carbon dioxide bubbles, which are ideal for contrast‐enhanced ultrasound imaging of acidic systems such as tumors.

中文翻译：

对比增强超声成像：具有仿生涂层的气体产生，pH响应的碳酸钙混合颗粒，用于对比增强超声成像（第二部分，系统特性2/2020）

在文章1900471中，Boon Mian Teo及其同事提出了一种具有仿生红细胞（RBC）膜涂层的聚多巴胺/牛血清白蛋白/碳酸钙（PDA / BSA / CaCO ₃）混合颗粒系统。该粒子系统结合了RBC膜调节蛋白质电晕形成的功能和CaCO ₃的pH敏感性，产生超回声的二氧化碳气泡，非常适合于酸性系统（如肿瘤）的超声造影对比。

更新日期：2020-02-20

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