BACKGROUND Chronic cough due to chronic bronchitis (CB) causes significant impairment in quality of life and effective treatment strategies are needed. We conducted a systematic review on the management of chronic cough due to CB to update the recommendations and suggestions of the CHEST 2006 guideline on this topic. METHODS This systematic review asked three questions: 1. "What are the clinical features of the history that suggest a patient's cough-phlegm syndrome is due to chronic bronchitis?"2. "Can treatment of stable chronic bronchitis improve or eliminate chronic cough?"3. "Can therapy that targets chronic cough due to chronic bronchitis prevent or reduce the occurrence of acute chronic bronchitis exacerbations?" Studies of adult patients with CB were included and assessed for relevance and quality. Based upon the systematic review, guideline suggestions were developed and voted on using the American College of Chest Physicians organization methodology. RESULTS The search strategy used an assortment of descriptors and assessments to identify studies of chronic cough due to CB. CONCLUSIONS The evidence supporting the management of chronic cough due to CB is limited overall and of low quality. This document provides guidance on treatment by presenting suggestions based on the best currently available evidence and identifies gaps in our knowledge and areas for future research.

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慢性支气管炎引起的慢性咳嗽：CHEST 专家小组报告

背景 慢性支气管炎 (CB) 引起的慢性咳嗽会导致生活质量显着受损，因此需要有效的治疗策略。我们对 CB 引起的慢性咳嗽的管理进行了系统评价，以更新 CHEST 2006 指南中关于该主题的推荐和建议。方法 本系统评价提出了三个问题： 1.“有哪些病史的临床特征表明患者的咳痰综合征是由慢性支气管炎引起的？”2．“稳定型慢性支气管炎的治疗能否改善或消除慢性咳嗽？”3．“针对慢性支气管炎引起的慢性咳嗽的治疗能否预防或减少急性慢性支气管炎恶化的发生？” 纳入了成年 CB 患者的研究，并评估了相关性和质量。基于系统评价，使用美国胸科医师学会组织方法制定指南建议并进行投票。结果 搜索策略使用了各种描述符和评估来确定 CB 引起的慢性咳嗽的研究。结论 支持治疗 CB 引起的慢性咳嗽的证据总体有限且质量低。本文件通过根据目前可用的最佳证据提出建议来提供治疗指导，并确定我们知识和未来研究领域的差距。结论 支持治疗 CB 引起的慢性咳嗽的证据总体有限且质量低。本文件通过根据目前可用的最佳证据提出建议来提供治疗指导，并确定我们知识和未来研究领域的差距。结论 支持治疗 CB 引起的慢性咳嗽的证据总体有限且质量低。本文件通过根据目前可用的最佳证据提出建议来提供治疗指导，并确定我们知识和未来研究领域的差距。