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The stress of being alone: Removal from the colony, but not social subordination, increases fecal cortisol metabolite levels in eusocial naked mole-rats.
Hormones and Behavior ( IF 2.5 ) Pub Date : 2020-02-25 , DOI: 10.1016/j.yhbeh.2020.104720
Phoebe D Edwards 1 , Skyler J Mooney 2 , Curtis O Bosson 3 , Ilapreet Toor 4 , Rupert Palme 5 , Melissa M Holmes 6 , Rudy Boonstra 7
Affiliation  

In many social species, hierarchical status within the group is associated with differences in basal adrenocortical activity. We examined this relationship in naked mole-rats (Heterocephalus glaber), eusocial rodents with arguably the most extreme social hierarchies of all mammals. This species lives in colonies where breeding is restricted to one socially dominant 'queen' and her male consorts, and all other individuals are reproductively suppressed 'subordinates'. The relationship between cortisol and social status in naked mole-rats has not fully been elucidated, as prior results on this topic have been contradictory. We used non-invasive feces sampling to measure baseline cortisol levels in eight laboratory colonies of naked mole-rats, to either replicate or reject rank differences. First, we successfully validated an assay to measure fecal cortisol metabolites (FCMs). Removal from the colony for the validation experiment, either alone or with an opposite sex conspecific, induced prolonged elevation of FCM levels on a scale of days to weeks. This increase in cortisol did not prevent the removed animals from sexually maturing. In colony-housed animals, we found no relationship between rank in the social hierarchy and FCM levels. Further, queens, breeding males, and reproductively suppressed subordinates all had equivalent FCM levels. We conclude that this species shows little evidence of the 'stress of dominance' or 'stress of subordination' and that reproductive suppression in naked mole-rats is not driven by elevated cortisol levels.

中文翻译:

孤独的压力:从殖民地中移出,而不是从属地移出,会增加正常社交裸鼠的粪便皮质醇代谢产物水平。

在许多社会物种中,群体内的等级地位与基础肾上腺皮质活动的差异有关。我们研究了裸鼠(鼠头畸形鼠),正常社交啮齿动物与所有哺乳动物中最极端的社会阶层之间的这种关系。该物种生活在殖民地,那里的繁殖仅限于一个具有社会主导地位的“女王”和她的雄性配偶,而其他所有个体都受到生殖抑制。裸mole鼠的皮质醇与社会地位之间的关系尚未得到充分阐明,因为有关该主题的先前研究结果是相互矛盾的。我们使用非侵入性粪便采样来测量裸mole鼠的八个实验室菌落的基线皮质醇水平,以重复或拒绝等级差异。第一,我们成功地验证了一种测定粪便皮质醇代谢物(FCM)的方法。单独或与异性同种菌种从菌落中移出进行验证实验,可导致FCM水平持续升高,持续数天至数周。皮质醇的增加并未阻止被移走的动物性成熟。在殖民地饲养的动物中,我们发现社会等级中的等级与FCM水平之间没有关系。此外,皇后,育种雄性和生殖抑制的下属都具有相等的FCM水平。我们得出的结论是,该物种很少显示出“主导压力”或“从属压力”的证据,裸naked鼠的生殖抑制不是由皮质醇水平升高驱动的。单独或与异性同种菌种从菌落中移出进行验证实验,可导致FCM水平持续升高,持续数天至数周。皮质醇的增加并未阻止被移走的动物性成熟。在殖民地饲养的动物中,我们发现社会等级中的等级与FCM水平之间没有关系。此外,皇后,育种雄性和生殖抑制的下属都具有相等的FCM水平。我们得出的结论是,该物种很少显示出“主导压力”或“从属压力”的证据,裸naked鼠的生殖抑制不是由皮质醇水平升高驱动的。单独或与异性同种菌种从菌落中移出进行验证实验,可导致FCM水平持续升高,持续数天至数周。皮质醇的增加并未阻止被移走的动物性成熟。在殖民地饲养的动物中,我们发现社会等级中的等级与FCM水平之间没有关系。此外,皇后,育种雄性和生殖抑制的下属都具有相等的FCM水平。我们得出的结论是,该物种很少显示出“主导压力”或“从属压力”的证据,裸naked鼠的生殖抑制不是由皮质醇水平升高驱动的。皮质醇的增加并未阻止被移走的动物性成熟。在殖民地饲养的动物中,我们发现社会等级中的等级与FCM水平之间没有关系。此外,皇后,育种雄性和生殖抑制的下属都具有相等的FCM水平。我们得出的结论是,该物种很少显示出“主导压力”或“从属压力”的证据,裸naked鼠的生殖抑制不是由皮质醇水平升高驱动的。皮质醇的增加并未阻止被移走的动物性成熟。在殖民地饲养的动物中,我们发现社会等级中的等级与FCM水平之间没有关系。此外,皇后,育种雄性和生殖抑制的下属都具有相等的FCM水平。我们得出的结论是,该物种很少显示出“主导压力”或“从属压力”的证据,裸naked鼠的生殖抑制不是由皮质醇水平升高驱动的。
更新日期:2020-02-25
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