BACKGROUND Bone metastasis is known to occur in some patients with cancer, usually in the spine, pelvis or ribs, and less than 0.01% of patients have metastases in the foot bone, so metatarsal metastasis is quite rare. The initial symptoms of osseous metastases are swelling, pain, or both. CASE PRESENTATION We report a 68-year-old man with solitary metatarsal metastasis 26 months after a diagnosis of renal clear cell carcinoma. The patient suffered intermittent swelling of his right foot and pain for one year due to trauma and was not treated. The doctor attributed the symptoms to trauma, administering massage therapy and a plaster cast to the patient at the local clinic. After reviewing the medical records, we found that this patient had a history of clear cell renal cell carcinoma. The patient underwent radiological examination and open biopsy of the first metatarsal bone of the right foot. These findings confirmed that the patient had a metatarsal metastasis from clear cell renal cell carcinoma. The patient subsequently underwent right foot amputation. No local recurrence or distant metastasis was found after a 6-month follow-up. CONCLUSION Clinicians should be aware of a history of renal cell carcinoma (RCC) and fully understand the patient's past medical history. When treating patients with clear cell renal cell carcinoma who have unresolving bony pain or swelling, clinicians should always keep in mind the possibility of bone metastasis of RCC.

中文翻译：

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透明细胞肾细胞癌的骨转移：一例报道并文献复习。

背景技术已知骨转移在一些癌症患者中发生，通常发生在脊柱，骨盆或肋骨中，并且少于0.01％的患者在脚骨中有转移，因此meta骨转移是非常罕见的。骨转移的最初症状是肿胀，疼痛或两者兼有。病例介绍我们报告了一名68岁的男性，在诊断出肾透明细胞癌后26个月发生了孤立的meta骨转移。由于外伤，患者的右脚间歇性肿胀和疼痛持续了一年，没有得到治疗。医生将症状归因于外伤，在当地诊所对患者进行了按摩治疗和抹灰。查阅病历后，我们发现该患者有透明细胞肾细胞癌病史。该患者接受了放射学检查，并对右脚的第一meta骨进行了活检。这些发现证实该患者患有透明细胞肾细胞癌的meta骨转移。患者随后接受了右脚截肢术。经过6个月的随访，未发现局部复发或远处转移。结论临床医生应了解肾细胞癌（RCC）的病史，并充分了解患者的既往病史。当治疗患有无法解决的骨痛或肿胀的透明细胞肾细胞癌患者时，临床医生应始终牢记RCC骨转移的可能性。患者随后接受了右脚截肢术。经过6个月的随访，未发现局部复发或远处转移。结论临床医生应了解肾细胞癌（RCC）的病史，并充分了解患者的既往病史。当治疗患有无法解决的骨痛或肿胀的透明细胞肾细胞癌患者时，临床医生应始终牢记RCC骨转移的可能性。患者随后接受了右脚截肢术。经过6个月的随访，未发现局部复发或远处转移。结论临床医生应了解肾细胞癌（RCC）的病史，并充分了解患者的既往病史。当治疗患有无法解决的骨痛或肿胀的透明细胞肾细胞癌患者时，临床医生应始终牢记RCC骨转移的可能性。