Voltage-gated sodium channel (Nav)1.5 is the predominantly expressed sodium channel in the myocardium. Mutations in the gene encoding Nav1.5 are associated with several types of cardiac arrhythmias. In their recent study, Jiang et al. provide a detailed structure of the rat Nav1.5, with major implications regarding its physiology, pharmacology, and pathophysiology.

中文翻译：

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说奶酪：心脏电动引擎的结构已捕获。

电压门控钠通道（Nav）1.5是心肌中主要表达的钠通道。编码Nav1.5的基因中的突变与几种类型的心律不齐有关。在他们最近的研究中，Jiang等。提供了大鼠Nav1.5的详细结构，主要涉及其生理学，药理学和病理生理学。